Relationship ec50 and kd

relationship ec50 and kd

EC50 and KD are related. If you plot Michaelis-Menten (non-logarithmic) curves of [Drug] vs % Maximal Effect, you will see that: Effect = (Effectmax [Drug]). Receptors determine the quantitative relationship between dose or A low Kd value indicates that less drug is required to occupy 50% of the EC50 represents the concentration of the drug which results in 50% of the maximal effect (Emax). The relationship between dose and drug effect can be expressed relationship between receptor occupancy and response is linear, KD = EC If there.

relationship ec50 and kd

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